There are a lot of other DMSO articles in the cue, but I made a decision I needed to do a much more comprehensive review of the literature first (manually going through ~50,000 studies and sorting the 5,000 comments I've received) as certain studies needed to write the future articles cannot be found in any other manner. I'm hoping to have the next one done at the end of December or start of January.
Thank you so much for your support and understanding.
Midwestern Doctor: Interestingly, I read Dr. Bresden’s first book 5 years ago, and clicked on the link for the book by Dr Doige. I found it on my shelf, but need to reread it. I remember it being fascinating. My question is whether reading is an activity that creates the necessary environment for a continued avoidance of dementia, since the synapses are constantly working? It would be good to know as it is much more compelling than any other activity, except healthy diet on a daily basis, and intermittent fasting.
Also, is DMSO sitting in the health food store waiting for me to buy it? Should I get a doctor’s approval first?
I would love to know how much oral DMSO to take prophylactically for cognitive decline (and how often). I am 65 110 lbs and would like to maintain (and possibly improve) my brain function as long as possible. I'm sure the answer is embedded in one of your articles but I would sure appreciate the answer as I have not located that information. Thank you for all you do!
Ive asked the same question many times. I dont think it’s legal for MD to respond perhaps? I sure wish there was a simple chart like so many other therapies stating: Age/Weight take this much for “dementia”…..ect
I do to! I am wanting to take DMSO for early intervention. My mother and two of her sisters passed away from dementia. I’m pretty good at the moment, but I’d like to have a preventative amount.
A more recent article from amd was published just the other day icymi, re Alzheimer's treatment involving UV light from a small amount of patient's blood in a transfusion, and reinjecting the blood back. Apparently it was highly successful but not profitable enough for AMA, who then manipulated successive tests to fail. Currently Germany and Russia are successfully using a similar treatment for many disorders including Alzheimers...
We purchase our DMSO from the DMSO Store on amazon. It was one of the brands given in another article. We have used this one both externally and internally for more than a year. We find a roll on version very useful for external use.
Sometimes all we have to do is Google search what we need. WMD has provided so much info for us so its up to us to find it. I use DuckDuckGo as a search engine and I simply searched a few words like DMSO benefits and look what I found with a 5 word search. It truly is not as complicated as we think. A lot of answers are in this handbook. Save it to your computer for future reference.
I frequently read several sources. The common dosing varies for everyone. I hear things like 1 tablespoon 2x per day or 1 tsp 3 x per day with water. Since it isn't an approved treatment by any officials, we have to use our common sense. No one can tell you how much to take. They would risk getting their license yanked if they did. So you have to take that risk yourself. We are in a new era of self medicating, since doctors don't have a clue. There is always a risk with self medicating. How much are you willing to gamble for your health? No one is responsible for you. I get tired of people asking for dosing because they resist taking responsibility for themselves.
I’m asking for information on how to take DMSO orally and how to find a doctor who will help you with it. Thanks very much for this information and for all you do!
Excellent article on DMSO healing benefits. What I don’t see from reading many of these articles is how DMSO is to be administered. I did do a reasesrch for DMSO for eye health (1-2 drops 1-2 times a day) but almost never am I able to find DMSO administration for other diseases / chronic ailments such as Alzheimers. Thank you.
MWD has written a series on DMSO, articles for particular issues as well as multiple instructions on various ways to use it for different issues, dosages, strengths and so on. They are all posted on the site.
No dosages given, no applications given on oral or IV given in any articles, it’s frustrating to read all of these articles with the most important information left out.
China recently developed a surgery (detailed here) to increase the lymphatic drainage from the brain. Due to its and low cost... There is a word missing here.
Very interesting article. Too late for my mom, she passed away in June, and dad probably would not have tried anything their own doctor did not subscribe to, which was a pity. I think one should try everything to help a suffering person! (and not euthanize them like Canada does nowadays)
The brain drains through the glymphatic system and replaces the cholesterol every 10 months. The brain makes its own cholesterol which a statin can reduce.
A family friend’s wife 80 years old and is in perfect health had two covid vaccines and developed severe Alzheimer’s disease within 6 months of the vaccine.
She’s in a special care home now.
She’s a vegetable basically.
Her primary care doctor dismissed the Alzheimer’s vaccine connection of course.
My friend had every booster. Now she isn't mentally as functional, though encouraging her (actually deliberately terrifying her) to get help may have kept her from going down quite as fast.
My brilliant aero space engineer cousin went full blown dementia within 2-3 moths of her mRNA injections and boosters, died in a car wreck she caused. She was going to a doctor appt 10 minutes away, got lost and drove hundreds of miles.
Based on my own experience, I believe whatever neurotoxin is in the shot, was also in the Covid bioweapon "flu". Although not as extreme, I have been experiencing cognitive issues since sickened with the bioweapon in July 2023.
Same here. It is astounding to me that so many people think our government is evil enough to make a kill shot, but not evil enough to engineer a kill virus [ or whatever it actually was ] I divide my life into before covid and after covid. Try Lumbrokinase.. It helped bring my antibodies down.
Thanks for the tip. It is my belief the government knew not everyone would comply with the shot, so they released the bioweapon via another method in order to effect as much of the population with it as possible. It's probably the reason for long Covid. Who ever had long term after effects from any normal flu seasons?
I think also Dr Kory has a protocol. The changed their name, so just typing it into the search bar would bring it up. Post viral infection has been around for a long time, but so have vaccines, so you never know. Before the 1800's, they might of called it something else. Beth [ Little Women ] died from complications of scarlet fever [ Strep ] Acute infections can cause lifetime disorders like autoimmune issues which then become a problem of their own. And remember- nature allowed the weak to die, so the paradigm shift of keeping people alive and passing their sick genetic codes onto multiple generations is an experiment in process. If you want to know how it's coming along, a slow stroll down the aisles of Walmart after 10:pm will educate you.
I did write about this previously that a friend died of Alzheimers from using an aluminum coffeemaker. Aluminum causes brain damage. It is in many products that people are using. . I warned her, about the aluminum in 1961. My father had sent me an article from St Catharine's Press in Ontario Canada... It is interesting that there were people who knew the danger of ingesting aluminum...68 years ago!
Excellent article! It’s time our medical schools stop embracing the concept that disease states always require chemical intervention! Time to put medical treatment back in the hands of physicians who are properly educated.
Understanding the physiology of the body has to be basic ! A brilliant physician that I met, who has now passed treated brain trauma with vitamin D and 3 Omega and other nutrients. He did a comparative study between his results and his cohort.. on a lifetime basis he saved 279 more patients who had to recover from traumatic brain injury, many of which were gunshot wounds. There is also a book called excitotoxins that discuss that artificial sweeteners like aspartame contribute to inflammation of the brain and the development of Alzheimer’s.. my friend‘s wife insisted on putting five equal packets into her cup of tea every day. She acquired Alzheimer’s.. it’s a slow process, but in my view is a chemical addiction and should’ve never been approved as a sweetener. There is a documentary published a good 25 years ago, called sweet misery and explains how it all came about which was a political act.! All you have to do is stand outside the lobby of a Costco and watch whose baskets are filled with a case of diet pop! they have the chemical addiction and can’t understand their weight gain is from the chemical addiction.
I will publish your article and include a reference to Dr. Leslie Matthews study .
He also was an international champion of the true value of vitamin D, and is responsible for convincing the FDA to include vitamin D content on food labels.
I believe the amyloid plaque theory has been debunked. Dr Christopher Exley (Substack) has shown toxic levels of aluminum in brain biopsies of Alzheimer and autism patients. 42 out of 45 vaccines have aluminum adjuvants. A macrophage can uptake aluminum and cross into the brain. Dr Robert Yokel (University of Kentucky) released a study May 2025 showing the average American adult consumes over 4lb of aluminum annually in food/drink. Dr Coimbra (Coimbra Protocol) uses high dose D3 to reverse Alzheimer, autism, MS, psoriasis with a high success rate. D3 is a prohormone that all tissue cells are looking for, including the brain. The brain is 50% cholesterol by dry weight which is replaced every 10 months. D (1,25dihydroxy) is used to make macrophages and immune signaling. Dr Exley has found that natural spring water high in silica chelates aluminum from the body.
I can also see the benefit of DMSO in batting many neurological diseases.
"Large population studies show that higher homocysteine levels predict faster cognitive decline and a greater risk of dementia [6][10]. These relationships are consistent, and they follow a clear pattern: the higher the level, the faster the decline.
"Researchers also understand why this happens. Homocysteine places strain on the brain in multiple ways. It injures the lining of small blood vessels, increases oxidative stress, disrupts methylation and accelerates the atrophy characteristic of Alzheimer’s disease [1][2].
"But the strongest evidence comes from intervention. In the Oxford trials, people with raised homocysteine who were given vitamin B6, B12 and folate experienced a remarkable slowing of brain shrinkage. In those with sufficient omega 3, the reduction in atrophy reached up to 73 per cent [3]. Cognitive decline slowed or even stopped for many participants [4]. When changing a factor changes the outcome, that factor can be considered causal."
#1 The majority of people with high homocysteine also have MTHFR genetic SNPs. #2 I am one of those people. My homocysteine is consistently high. I am 73, and I have experienced no mental decline.
If your homocysteine is high, the pressure in your eyes is most likely also high, what is called glaucoma.
Did you read the article in Substack that suggested silica helps clear lymphatic fluid in the brain? It mentioned Fiji water, which has high silica content. I don't have dementia but have been trying to see if I notice a difference. I do use DMSO on my dog with vestibular issues and it definitely helps.
Thanks! My hubby and I both struggle to get a good night's sleep most nights, so this could be helpful. Are you referring to an AMD article or someone else’s, and could you include a link?
If you have had a DMSO report you'd like to share, please do so here:
https://www.midwesterndoctor.com/p/the-remarkable-history-and-safety/comments
When they are posted in other places, despite my best efforts, they frequently get missed and don't make it up there.
Additionally, the most current information on using DMSO can be found in this article:
https://www.midwesterndoctor.com/p/dmso-heals-the-eyes-and-transforms
There are a lot of other DMSO articles in the cue, but I made a decision I needed to do a much more comprehensive review of the literature first (manually going through ~50,000 studies and sorting the 5,000 comments I've received) as certain studies needed to write the future articles cannot be found in any other manner. I'm hoping to have the next one done at the end of December or start of January.
Thank you so much for your support and understanding.
MD you are a miracle in yourself. Thank you for your articles, that certainly have helped numerous people!
thanks for your diligence and generosity, AMD!
Midwestern Doctor: Interestingly, I read Dr. Bresden’s first book 5 years ago, and clicked on the link for the book by Dr Doige. I found it on my shelf, but need to reread it. I remember it being fascinating. My question is whether reading is an activity that creates the necessary environment for a continued avoidance of dementia, since the synapses are constantly working? It would be good to know as it is much more compelling than any other activity, except healthy diet on a daily basis, and intermittent fasting.
Also, is DMSO sitting in the health food store waiting for me to buy it? Should I get a doctor’s approval first?
Thank you!!!
I would love to know how much oral DMSO to take prophylactically for cognitive decline (and how often). I am 65 110 lbs and would like to maintain (and possibly improve) my brain function as long as possible. I'm sure the answer is embedded in one of your articles but I would sure appreciate the answer as I have not located that information. Thank you for all you do!
Read the “link to the longer article” in the conclusion. It gives amounts and where to find pure DMSO.
I do believe I read that at some point, but I’ll go back - did I mention I have ADD also ☺️?
I must have missed that in the long article. Ill go back and look.
Weirdly my comment back to you about using dmso without a filter has disappeared….weird.
Ive asked the same question many times. I dont think it’s legal for MD to respond perhaps? I sure wish there was a simple chart like so many other therapies stating: Age/Weight take this much for “dementia”…..ect
I do to! I am wanting to take DMSO for early intervention. My mother and two of her sisters passed away from dementia. I’m pretty good at the moment, but I’d like to have a preventative amount.
A more recent article from amd was published just the other day icymi, re Alzheimer's treatment involving UV light from a small amount of patient's blood in a transfusion, and reinjecting the blood back. Apparently it was highly successful but not profitable enough for AMA, who then manipulated successive tests to fail. Currently Germany and Russia are successfully using a similar treatment for many disorders including Alzheimers...
We purchase our DMSO from the DMSO Store on amazon. It was one of the brands given in another article. We have used this one both externally and internally for more than a year. We find a roll on version very useful for external use.
Sometimes all we have to do is Google search what we need. WMD has provided so much info for us so its up to us to find it. I use DuckDuckGo as a search engine and I simply searched a few words like DMSO benefits and look what I found with a 5 word search. It truly is not as complicated as we think. A lot of answers are in this handbook. Save it to your computer for future reference.
https://www.eden-shop.eu/wp-content/uploads/2020/06/Scott-Archie-DMSO-Handbook.pdf
Sorry Lena, not one sentence on dosage. Just confirming what we already know - that it helps and the earlier you start the better.
I frequently read several sources. The common dosing varies for everyone. I hear things like 1 tablespoon 2x per day or 1 tsp 3 x per day with water. Since it isn't an approved treatment by any officials, we have to use our common sense. No one can tell you how much to take. They would risk getting their license yanked if they did. So you have to take that risk yourself. We are in a new era of self medicating, since doctors don't have a clue. There is always a risk with self medicating. How much are you willing to gamble for your health? No one is responsible for you. I get tired of people asking for dosing because they resist taking responsibility for themselves.
I’m asking for information on how to take DMSO orally and how to find a doctor who will help you with it. Thanks very much for this information and for all you do!
Check out my answer and link above.
You'll search high and low to find such a doctor. My guess, maybe 6-8 in the United States.
Excellent article on DMSO healing benefits. What I don’t see from reading many of these articles is how DMSO is to be administered. I did do a reasesrch for DMSO for eye health (1-2 drops 1-2 times a day) but almost never am I able to find DMSO administration for other diseases / chronic ailments such as Alzheimers. Thank you.
MWD has written a series on DMSO, articles for particular issues as well as multiple instructions on various ways to use it for different issues, dosages, strengths and so on. They are all posted on the site.
You can find all of it on this substack. Just go to her archived list. Sometimes we just have to look.
No dosages given, no applications given on oral or IV given in any articles, it’s frustrating to read all of these articles with the most important information left out.
Read the link to the longer article in the conclusion. It gives dosages in the conclusion.
China recently developed a surgery (detailed here) to increase the lymphatic drainage from the brain. Due to its and low cost... There is a word missing here.
Very interesting article. Too late for my mom, she passed away in June, and dad probably would not have tried anything their own doctor did not subscribe to, which was a pity. I think one should try everything to help a suffering person! (and not euthanize them like Canada does nowadays)
Fixed, apologies.
The brain drains through the glymphatic system and replaces the cholesterol every 10 months. The brain makes its own cholesterol which a statin can reduce.
My great-grandmother 1962, my grandmother 1989, a great aunt 1990's, my mother Sept 2018, my aunt Feb 2025.
The missing word (guessing) appears to be efficacy (?).
"Due to its efficacy and low cost..."
A family friend’s wife 80 years old and is in perfect health had two covid vaccines and developed severe Alzheimer’s disease within 6 months of the vaccine.
She’s in a special care home now.
She’s a vegetable basically.
Her primary care doctor dismissed the Alzheimer’s vaccine connection of course.
My friend had every booster. Now she isn't mentally as functional, though encouraging her (actually deliberately terrifying her) to get help may have kept her from going down quite as fast.
My brilliant aero space engineer cousin went full blown dementia within 2-3 moths of her mRNA injections and boosters, died in a car wreck she caused. She was going to a doctor appt 10 minutes away, got lost and drove hundreds of miles.
Based on my own experience, I believe whatever neurotoxin is in the shot, was also in the Covid bioweapon "flu". Although not as extreme, I have been experiencing cognitive issues since sickened with the bioweapon in July 2023.
Same here. It is astounding to me that so many people think our government is evil enough to make a kill shot, but not evil enough to engineer a kill virus [ or whatever it actually was ] I divide my life into before covid and after covid. Try Lumbrokinase.. It helped bring my antibodies down.
Thanks for the tip. It is my belief the government knew not everyone would comply with the shot, so they released the bioweapon via another method in order to effect as much of the population with it as possible. It's probably the reason for long Covid. Who ever had long term after effects from any normal flu seasons?
I think also Dr Kory has a protocol. The changed their name, so just typing it into the search bar would bring it up. Post viral infection has been around for a long time, but so have vaccines, so you never know. Before the 1800's, they might of called it something else. Beth [ Little Women ] died from complications of scarlet fever [ Strep ] Acute infections can cause lifetime disorders like autoimmune issues which then become a problem of their own. And remember- nature allowed the weak to die, so the paradigm shift of keeping people alive and passing their sick genetic codes onto multiple generations is an experiment in process. If you want to know how it's coming along, a slow stroll down the aisles of Walmart after 10:pm will educate you.
If I were you I would be looking into detoxing the spike.
Perhaps you’re experiencing excessive spike.
There is a test that Labcorp offers to check your spike levels.
I heard that it’s about $70.00 dollars.
There you go again; being skeptical of repeat convicted felons creating the best of injectables for us all.
Chuckle of the day.
I thought of Crocodile Dundee ( " Now this is a knife " ) when reading about sleeping pills :
" ....and have a variety of issues.......( e.g., they make users 2-5 times as likely to die.
Death, " Now this is an issue !! ) LOL.
I did write about this previously that a friend died of Alzheimers from using an aluminum coffeemaker. Aluminum causes brain damage. It is in many products that people are using. . I warned her, about the aluminum in 1961. My father had sent me an article from St Catharine's Press in Ontario Canada... It is interesting that there were people who knew the danger of ingesting aluminum...68 years ago!
Silica rich water helps remove Al. There are several on the market. I take BioSil, which has the same version of silica these waters have.
Fiji water has a high level of silica I understand. Also Volvic.
Mouzer, on Vitacost's website, I noticed that they offer different BioSil products. Can you tell me the specific BioSil product you use? Thank you.
liquid collagen generator, nothing added
Thank you!
This article is amazing and informative. More than we’ll ever hear from the propaganda machine! Thank you! 😊
Excellent article! It’s time our medical schools stop embracing the concept that disease states always require chemical intervention! Time to put medical treatment back in the hands of physicians who are properly educated.
Understanding the physiology of the body has to be basic ! A brilliant physician that I met, who has now passed treated brain trauma with vitamin D and 3 Omega and other nutrients. He did a comparative study between his results and his cohort.. on a lifetime basis he saved 279 more patients who had to recover from traumatic brain injury, many of which were gunshot wounds. There is also a book called excitotoxins that discuss that artificial sweeteners like aspartame contribute to inflammation of the brain and the development of Alzheimer’s.. my friend‘s wife insisted on putting five equal packets into her cup of tea every day. She acquired Alzheimer’s.. it’s a slow process, but in my view is a chemical addiction and should’ve never been approved as a sweetener. There is a documentary published a good 25 years ago, called sweet misery and explains how it all came about which was a political act.! All you have to do is stand outside the lobby of a Costco and watch whose baskets are filled with a case of diet pop! they have the chemical addiction and can’t understand their weight gain is from the chemical addiction.
I will publish your article and include a reference to Dr. Leslie Matthews study .
He also was an international champion of the true value of vitamin D, and is responsible for convincing the FDA to include vitamin D content on food labels.
Aluminum and Alzheimer's
https://drchristopherexley.substack.com/p/alzheimers-disease-is-caused-by-aluminium
I believe the amyloid plaque theory has been debunked. Dr Christopher Exley (Substack) has shown toxic levels of aluminum in brain biopsies of Alzheimer and autism patients. 42 out of 45 vaccines have aluminum adjuvants. A macrophage can uptake aluminum and cross into the brain. Dr Robert Yokel (University of Kentucky) released a study May 2025 showing the average American adult consumes over 4lb of aluminum annually in food/drink. Dr Coimbra (Coimbra Protocol) uses high dose D3 to reverse Alzheimer, autism, MS, psoriasis with a high success rate. D3 is a prohormone that all tissue cells are looking for, including the brain. The brain is 50% cholesterol by dry weight which is replaced every 10 months. D (1,25dihydroxy) is used to make macrophages and immune signaling. Dr Exley has found that natural spring water high in silica chelates aluminum from the body.
I can also see the benefit of DMSO in batting many neurological diseases.
"Large population studies show that higher homocysteine levels predict faster cognitive decline and a greater risk of dementia [6][10]. These relationships are consistent, and they follow a clear pattern: the higher the level, the faster the decline.
"Researchers also understand why this happens. Homocysteine places strain on the brain in multiple ways. It injures the lining of small blood vessels, increases oxidative stress, disrupts methylation and accelerates the atrophy characteristic of Alzheimer’s disease [1][2].
"But the strongest evidence comes from intervention. In the Oxford trials, people with raised homocysteine who were given vitamin B6, B12 and folate experienced a remarkable slowing of brain shrinkage. In those with sufficient omega 3, the reduction in atrophy reached up to 73 per cent [3]. Cognitive decline slowed or even stopped for many participants [4]. When changing a factor changes the outcome, that factor can be considered causal."
https://foodforthebrain.org/the-midlife-biomarker-proven-to-drive-alzheimers-and-how-to-bring-it-down/?utm_source=Food+for+the+Brain+Foundation&utm_campaign=8c6e5ced46-sunday_blast_7_12_25_COPY_03&utm_medium=email&utm_term=0_47a885e6cd-8c6e5ced46-290045410&mc_cid=8c6e5ced46&mc_eid=76fd273bd9
#1 The majority of people with high homocysteine also have MTHFR genetic SNPs. #2 I am one of those people. My homocysteine is consistently high. I am 73, and I have experienced no mental decline.
If your homocysteine is high, the pressure in your eyes is most likely also high, what is called glaucoma.
If you can lower your homocysteine level, the pressure in your eyes will go down also
Did you read the article in Substack that suggested silica helps clear lymphatic fluid in the brain? It mentioned Fiji water, which has high silica content. I don't have dementia but have been trying to see if I notice a difference. I do use DMSO on my dog with vestibular issues and it definitely helps.
BioSil has the same type of silica. I use it as a liquid though it comes in pill form. I put it in juice.
Thanks! My hubby and I both struggle to get a good night's sleep most nights, so this could be helpful. Are you referring to an AMD article or someone else’s, and could you include a link?
I was afraid someone would ask and that I hadn't saved it. I did find it!
https://open.substack.com/pub/unbekoming/p/alzheimers-disease-understanding?r=r86jd&utm_medium=ios
Thank you! I'm sure it'll help others as well.